hamilton bennett moderna bio

[2] Boston audiences of 1890 gasped when this photograph was projected as a magic lantern slide. Some said it would divert resources from thriving areas of research and reprioritize other lucrative programs, while betting on a yet unproven vaccine technology. All rights reserved. Facing down a pandemic the likes of which the world hadnt seen in a century, Bennett, senior director of vaccine access and partnerships at Moderna, was tasked with developing a COVID vaccine even before the viruss genome had been sequenced. Haller wasnt fazed. "I think when every person in primarily the U.S, but also in our global space has access to a vaccine that's when I think I'm going to be able to breathe, say, 'OK, we've done it,'" she concluded. Senior Director, Vaccine Access and Partnerships, CA Notice at Collection and Privacy Notice, Do Not Sell/Share My Personal Information. He knew that if Seattle became too much of a hot spot, it could upend the trial in many ways. Nevertheless, Bennett pressed on in his profession, selling gift shop type items from his studio to attract more customers and continuing as a professional landscape photographer until his death from Bright's disease in 1908. Bennett was born in Farnham, Quebec and raised in Brattleboro, Vermont. It was 7 p.m. on a Friday, and the streets below in Kendall Square had already emptied out for the weekend when Graham asked Bennett if Moderna would be interested in using the new virus to test the companys accelerated vaccine-making capabilities. On the radio, the news was wall-to-wall coronavirus. But I also know that shit happens. So as upbeat as he felt about Modernas efforts to build a vaccine, he was gripped with fear every day of the manufacturing process that something would go wrong. From that point on, every time she received a new, accelerated timeline, shed simply stand up, wipe the old one off the giant whiteboard that extended the length of her desk, and mark the new one down. Hamilton Bennett works in the Research industry. "We've come a long way in 12 months," Bennett told ABC News in an exclusive interview for "The Shot: Race for the Vaccine," a one-hour special edition of "20/20.". At Moderna, we believe messenger RNA, or mRNA, is the "software of life. They are also relatively easy to scale and produceyou can design any mRNA vaccine in the world on a computer and manufacture it in a single facility regardless of what disease it is for. Bancel forwarded Grahams email to Hamilton Bennett, an energetic and idealistic 35-year-old whod spent the previous three years as program leader on Modernas vaccine portfolio. ASSOCIATE DIRECTOR, VACCINE ACCESS AND PARTNERSHIPS, MODERNA THERAPEUTICS, INC Cambridge, Massachusetts, United States Hamilton Bennett (she/her) is the Senior Director of Vaccine Access and Partnerships at Moderna, a company pioneering messenger RNA (mRNA) therapeutics and vaccines. Agriculture & Environment. During dinner, the dings of incoming text messages punctuated his conversation. On March 11, Italy closed for business. Drug Development & Review . Bancel forwarded Graham's email to Hamilton Bennett, an energetic and idealistic 35-year-old who'd spent the previous three years as program leader on Moderna's vaccine portfolio. Hamilton Bennett's research while affiliated with Moderna and other places Overview What is this page? Can you make any sense of the viral outbreak going on in China? Bancel pecked out on his tablet. Moderna, the little-known biotech company based in Cambridge, Massachusetts, has been at the forefront of vaccine development since the outbreak. Chinese officials had closed the airport, bus terminals, and train stations, effectively shuttering a city of 11 million. Three days later, on January 10, Bennett was on a previously scheduled call with Graham when the subject of Chinas low-level viral outbreak came up. He lunged for it. [3] After the war, the wound prevented Bennett from returning to carpentry, so in 1865 he bought the Kilbourn City photography studio operated by Leroy Gates and began a career as a photographer. The news sent Modernas stock price so high that Bancel became a billionaire overnight. Each day, as the coronavirus advanced around the globe, the quest for a vaccine took on an even higher level of importance and became a greater sense of pride for workers at the companyeven for some far away from the manufacturing room floor. Big Pharma had officially joined the race. Photo via AP Photo/Ted S. Warren. Please Note: All American Speakers Bureau is a full-service talent booking agency providing information on booking Hamilton Bennett for speaking engagements, personal appearances and corporate events. It was as if overnight, Moderna had been bumped up to the adults table and it was Christmas dinner. Moderna already had a template to work from, having spent several years designing experimental mRNA vaccines for the Middle East respiratory syndrome coronavirus (MERS-CoV) and the Zika virus. Bancel was nervous. On February 7, the chief of technical operations and quality, industry veteran Juan Andres, went to the cafeteria at the Norwood plant for lunch. Bennett said. Bennett went back into the software and updated everyones timeline. 1201 New York Avenue NW, Suite 1300, Washington, DC, 20005 202-962-9200, BIO Intellectual Property Counsels Committee Conference. We will show you what we can do.. Offers may be subject to change without notice. To learn more, visit www.modernatx.com.This Moderna page is not the appropriate place to report adverse events (side-effects) for any products. The plan worked. vaccine. In addition, what if a vaccine wasnt needed? As soon as she walked into her house, though, she dropped her bag on the floor and fell into a puddle of tears. Pharma companies had gotten left holding the bag during other novel viral epidemics, investing heavily to develop vaccines only to watch as the disease fizzled out on its own. Just two months later, Moderna began its NIH-led phase 1 study. Her research and development experience and laser-like focus on COVID helped Moderna get its vaccine into early clinical trials within two monthsand receive FDA emergency use authorization by December. Bancel shook his head. Vaccines & Biodefense. She holds graduate degrees from the University of Washington in Environmental Health and Microbiology, and a certificate in Epidemiology from the London School of Hygiene and Tropical Medicine. Bennett received much attention for his advanced techniques, and was commissioned by the Chicago, Milwaukee & St. Paul Railroad to photograph the landscape along the company's track in Wisconsin. However, very little is known about the 35-year-old executive who has been spearheading the race to make Moderna's Covid-19 vaccine widely available. People lost their jobs, diagnoses soared, and the body count rose. Haller picked up the phone and called her mother. Unlike more traditional vaccines, which consist of weakened or inactivated forms of a virus, thus stimulating the body's immune response to create antibodies, a vaccine using mRNA sends a set of instructions into cells to teach them to make a protein, which will trigger an immune response inside our bodies to fight off the disease. Normally, he would never take a call at a moment like that, but Bancel usually only communicated with him through textsunless, that is, the matter was urgent. Of those that do, not all will make it to Phase 3, and no one knows whichif anywill ultimately prove effective and ostensibly save the world. mRNA-1273 is currently in a Phase 2 clinical trial with a trajectory towards Phase 3 efficacy evaluation. Since then, Moderna's vaccine has been given to millions of people worldwide. Can I call you right now?. Over several days, Bancel gathered with colleagues to plot out a foolproof shipping strategy. And if we don't do it, maybe no one else will," Bennett said, while recalling her reasoning at the time. At the time, 35-year-old Hamilton Bennett, the senior director of vaccine access and partnerships at Moderna, a small, then-relatively unknown biotech company based in Cambridge,. On the 14th and final day of the sterility test, the quality control team told Bancel they would not have any news until later that evening. Bennett argued to go for the real vaccine. Moderna had worked with Graham and the NIH over the past few years on its quest to bring a whole new class of vaccines to market. "We believe that our platform is going to make a difference, and we believe that we're uniquely capable of responding to this pandemic. The Journal contained enough business news to keep Bancel occupied, but it was another headline that grabbed his attentionabout the outbreak of a mysterious illness in China. Under the lights on the loading dock, they secured the precious cargo in the truck and closed the door. Several days later, on a moonlit Friday night, Bancel wheeled his suitcase into Terminal D at Logan Airport and checked into a red-eye bound for Zurich. The area quickly became a destination for sightseers eager to leave behind the bustle of the city. In his world, a global pandemic was about to descend like a biblical plague, and whatever distractions the vaccine caused internally at Moderna were irrelevant. He built himself a portable darkroom, and then towed it, his camera, and other necessary equipment with him across the local countryside taking pictures. We don't have to grow a virus and then extract proteins from it, your body becomes its own little bio factory and creates the vaccine for you." David L. Ryan/Boston Globe via Getty Images, FILE, Adam Glanzman/Bloomberg via Getty Images, FILE, New book busts myths, answers common questions about menopause. Seven days a week, she stayed late at the office before driving home to Malden, where her husband had long ago gone to sleep. Hamilton maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science . Just two months later, Moderna began its NIH-led phase 1 study. By the weekend of January 25, just days after Moderna decided to go full steam ahead, he was convinced the world was going to need a vaccine for this virus. In contrast, Modernas vaccines contain an engineered strand of messenger RNA, which tells the bodys cells to produce a very specific part of a pathogen that will ignite an immune response. Check that you typed the address correctly, go back to your previous page or try using our site search to find something specific. The next day, she was back in the office at 7 a.m. Everyone at Moderna was on tenterhooks waiting for manufacturing to finish making the vaccine. Moderna was perfectly poised to respond and had an obligation to do so, she said. At 8:30 a.m. one morning during the early days of the project, a member of her team delivered the estimated timeline: 120 days. Andreswho was expecting something more along the lines of, Do you want lettuce and tomato on that?was taken aback. But it wasnt until a few days later, as the deaths in Kirkland mounted, that Haller began to really worry about her 85-year-old stepdad. Company. Before she knew it, they had halved the time to 60 days. Moderna's senior director of vaccine access and partnerships at Moderna, is 35-year-old Hamilton Bennett. Hamilton Bennett's HQ phone number is +1 617-714-6500. As he spent time with two prominent infectious-disease experts from Europe, they were receiving a constant stream of information from their contacts on the ground in China, including Wuhan, the epicenter of the outbreak. Moderna already had a template to work from, having spent several years designing experimental mRNA vaccines for the Middle East respiratory syndrome coronavirus (MERS-CoV) and the Zika virus. On January 23, Moderna and CEPI went public with the newsbut Bancels attention was focused on the information coming out of Wuhan that day. As he followed the news out of China, though, he felt a rising sense of urgency. In the midst of much uncertainty and chaos, Bennett, has emerged as one of the unsung heroes of the pandemic, working feverishly and tirelessly behind the scenes throughout the year to help engineer a vaccine that could potentially save millions of lives. Senior Director, Vaccine Access and Partnerships. Like Moderna, both of these groups utilize novel platforms that can quickly make vaccines without using the virus itself. "The world was looking at us because we had started the first study in the U.S. We had done it faster than anyone before had ever done it. He clicked on the story and scrolled down looking for details: 59 people sick with viral pneumonia. Up from 27 from just days before. Bennett described. biotechnology: biological products (no diagnostic substances), Sr. Project Manager, Clinical Development, Senior Director, Facilities & Engineering | Global Project Lead, Find verified emails and direct dial mobile numbers of contacts on LinkedIn, and sync them with your CRM instantly, Senior Director, Vaccine Access and Partnerships. They wanted to see how it would play out. For one thing, because mRNA vaccines dont contain a pathogen, they are thought to be safer than traditional vaccines. The news only strengthened Hallers resolve to participate in Modernas trials. The site that the NIH had chosen for the trialthe only site it had selectedwas in Seattle. She felt fortunate to have a job she could do from home, and because her hours were flexible, she knew she could make it to the dozen or so required appointments. All rights reserved. We are going to need a vaccine for this, he wrote. Moderna and Dr. Barney Graham, deputy director of the Vaccine Research Center at the NIH, had discussed executing a prototype project for a mRNA vaccine in 2020. And stand up for science. If you're a human and see this, please ignore it. Since then, Moderna has produced more than 300 million doses and has played a major role in curbing the pandemic. The team was able to quickly identify the spike protein and understand how to engineer and stabilize it to induce a strong immune response, and when Bennett's team and the researchers at the NIH saw they had designed the same sequence independently, they felt confident in their findings. Later that evening, he was standing in his kitchen when his phone dinged again. When data from the first phases of Moderna's clinical trial revealed the vaccine candidate had generated a protective immune response, it was a "sigh of relief" from the team -- but there was "no time to appreciate it," Bennett said. It was no longer just an interesting experiment on a clinical scale. Bennett also took pictures outside the state, photographing an ice palace in St. Paul, Minnesota and the World's Columbian Exposition in Chicago, Illinois. We will see what they can do, he said. But if the risk paid off, the reward would be substantial: It could shave weeks, even months, off the timeline. As he brainstormed options with Andressomeone Bancel affectionately calls as paranoid as he istheir solutions quickly spun out of hand. It almost felt like the world around us was shifting, but for those of us on the program, our entire world was the program," Bennett said. Just two days after the first complete genome of the virus was mapped and publicly posted online in early January, Moderna's COVID-19 vaccine candidate, mRNA-1273, was finalized. As he huddled next to the heater, he searched Google for international flights out of Wuhan. To Bancel, meanwhile, the sheer act of debating whether to move forward struck him as absurd in light of what he was learning at Davos. 36. On March 30, Johnson & Johnson announced it was investing a billion dollars for Janssen to create a billion doses of Barouchs vaccine if it proved successful. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of a global pandemic that has led to more than 2.8 million deaths worldwide. He didnt like the sound of it one bit, so he copied the story link and pasted it into an email directed at Barney Graham, deputy director of the Vaccine Research Center at the National Institutes of Health. Haller felt a small prick in her left arm, followed by the sensation of the syringes cool liquid contents slipping into her biceps, and the rising satisfaction of knowing that she had finally found a way to do something. Early Monday morning, Modernas scientists went to work on a COVID-19 vaccine. In the meantime, at Modernaand for all of usthe clock is still ticking. Corbett's academic biography notes " the vaccine concept incorporatedin mRNA-1273 was designed by Dr. Corbett's NIH team from viral sequence and rapidly deployed to industry partner, Moderna, Inc." 19 According to Dr.Corbett, an earlier partnershipwith Moderna focused on the MERS coronavirus helped acceleratetheSARS- -2 response. As new data shows kids in a mental health crisis, parents ask, where is the help for kids? Upstairs, her kids were still asleep when she slid into her car and drove downtown. Just about the last place he needs to be is in a fast-food restaurant in Kirkland, she told her mom. He didn't have to go far to find impressive scenery, for the Wisconsin River Dells, a gorge with numerous sandstone formations, was just outside Kilbourn City. He was technically on vacation at his home in the south of France, but even on his days off, Bancel didnt sleep much. My hope for the world is that many of us get to the finish line, so we can stop this thing, Bancel says. Human Health. Then you wait for the animal data before you manufacture a vaccine for human trials. As portable film cameras became widespread in the 1890s, Bennett's career declined somewhat because tourists coming to see the Dells were able to take their own souvenir photos and no longer needed Bennett's postcards or portraits. That weekend the Chinese government posted the viruss sequence. She signed away. "I think I emailed my team every six hours, Saturday, Sunday saying, 'Have you designed the vaccine sequence yet?'" Aside from shipping, the sterility test was Bancels biggest worry. On the flip side, what if it really was needed? The potential implications of using mRNA as a drug are significant and far-reaching and could meaningfully improve how medicines are discovered, developed and manufactured. On February 6, Bennett had just left work when her car broke down. The data showed sky-high infection rates and mounting evidence that human-to-human transmission was well under way. In January, with exponential growth in infection rates in the city of Wuhan, China, and increasing evidence of high community transmission, Moderna's leadership acknowledged that the outbreak was a serious threat and asked Bennett to begin working on a COVID-19 vaccine as soon as the new virus's genome sequence was obtained. Hamilton Bennett's Professional Contact Details, Hamilton Bennett's Current Company Details, Hamilton Bennett's Work History and Education, Frequently Asked Questions about Hamilton Bennett. Strengthening the Bioeconomy. Growing Trust in Innovation. It was showtime. Across the Charles in Boston, there was one scientist who thought Big Pharma should get on boardand he had a feeling he could make it happen. The model turned Hong Kong film actress lives in Singapore. As Haller waited for the study to start, the deadly virus continued to spread. Not so long ago, one of Modernas products was left outside of cold storage once it was no longer in the companys hands, and the entire load had to be tossed in the trash. Title. That night, she ditched her vehicle near the office, called an Uber, and managed to hold it together the whole ride home. Adam Glanzman/Bloomberg via Getty Images, FILE, Do Not Sell or Share My Personal Information. The company had also been working for years in conjunction with the National Institutes of Health (NIH) on bringing a new class of vaccines to market. The promising news not only shot Modernas share price higher, but sent the entire stock market soaring by more than 900 points. In Davos, he hammered out a collaboration agreement with the Coalition for Epidemic Preparedness Innovations (CEPI), a foundation that finances infectious-disease research, to produce Phase 1 of the vaccine. A major advantage of mRNA is that it is very easy to manufacture these RNA sequences once researchers know the sequence of the viral protein they want to target. International. Less than a year ago, little was known about the mysterious virus that was sickening dozens in China and spreading rapidly unbeknownst to people across the globe. "I think what we've done is show the world that it's OK to be bold and to stand up and say, 'We can do this,'" said Bennett, adding that it will likely be months before she will be able to fully appreciate her team's hard work. Usually partnerships between academic labs and pharma take months to negotiate. Barouch had worked in the past with Janssen, the pharmaceutical arm of Johnson & Johnson. Moderna and Dr. Barney Graham, deputy director of the Vaccine Research Center at the NIH, had discussed executing a prototype project for a mRNA vaccine in 2020. Almost overnight, Bostons streets became eerily quiet as life as we knew it drifted further into a new normal. Hamilton Bennett's business email address is h**@modernatx.com. There is no gray area; it is either 100 percent sterile or you are done, he says. News of the first U.S. death and the spread of the coronavirus in Seattle were also on Bancels mind, but for slightly different reasons. In the midst of much uncertainty and chaos, Bennett emerged as one of the unsung heroes of the pandemic, working feverishly and tirelessly behind the scenes throughout the year to help engineer a vaccine that could potentially save millions of lives. Join BIO as we champion for bringing new treatments to patients with serious medical conditions and to support policies that promote innovation and improve patient access. Almost twenty years later, hes still baby faced and his hair is still jet black, though hes no longer always the youngest guy in the room. What he saw sent shockwaves down to the tips of his fingers: an endless list of flights to nearly every corner of the world. Its going to be the 1918 flu pandemic. View Hamilton Bennett's business profile as Senior Director, Vaccine Access & Partnerships at Moderna. Bancel, of course, hopes that Modernas vaccine works, but he doesnt want to be alone in the winners circle. Dan Barouch, who heads the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, is something of a prodigy, having run his own research lab since the age of 29. At the time, 35-year-old Hamilton Bennett, the senior director of vaccine access and partnerships at Moderna, a small, then-relatively unknown biotech company based in Cambridge, Massachusetts, did not anticipate that her team's years of work would soon be thrust into the global spotlight when Moderna became the first American company to jump into the race to a coronavirus vaccine. Later that day, Bancels phone pinged with an email from Graham at the NIH. Hamilton Bennett, Senior Director of Vaccine Access & Partnerships: "Your body gets sort of the software it needs to make its own protein. Since time was of the essence, Moderna decided to do all of the steps simultaneously. Afeyan apologized to his daughter, quickly rose from the table, and without putting on his coat walked out of the restaurant and onto Mass. "I think I emailed my team every six hours, Saturday, Sunday saying, 'Have you designed the vaccine sequence yet?'" That was in January 2020, just a month after the first reports of a mysterious new lung illness in China. He has spent most of his career seeking one for HIV and has worked on one for Ebola, too. Clearly, this is coming, and it's coming to the states.'". Bennett was no stranger to working at breakneck speed. When data from the first phases of Moderna's clinical trial revealed the vaccine candidate had generated a protective immune response, it was a "sigh of relief" from the team -- but there was "no time to appreciate it," Bennett said. The same day, the sober-faced director-general of the World Health Organization faced the media and uttered the words no one wanted to hear: COVID-19 was officially a global pandemic. "We realized that [SARS-CoV-2] was our prototype and that this was a live run that we were moving through." Bennett, a self-described "public-health nerd" with a master's degree in environmental microbiology, had sought a job at the company after hearing it was working on mRNA-based vaccines for new.

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